CANCER INCIDENCE RATES



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CANCER INCIDENCE RATES
ABSTRACT
Among various diseases, cancer has become a big threat to human beings globally. As per Indian population census data, the rate of mortality due to cancer in India was high and alarming with about 806000 existing cases by the end of the last century. Cancer is the second most common disease in India responsible for maximum mortality with about 0.3 million deaths per year. This is owing to the poor availability of prevention, diagnosis and treatment of the disease. All types of cancers have been reported in Indian population including the cancers of skin, lungs, breast, rectum, stomach, prostate, liver, cervix, esophagus, bladder, blood, mouth etc. The causes of such high incidence rates of these cancers may be both internal (genetic, mutations, hormonal, poor immune conditions) and external or environmental factors (food habits, industrialization, over growth of population, social etc.). In view of these facts, the present article describes the status of various types of cancers in India and its comparison at global level. Besides, attempts have been made to describe the main causes of cancer along with their preventive measures. In addition to this, efforts have also been made to predict the effect of increasing number of cancer patients on the Indian economy.

INTRODUCTION
In spite of good advancements for diagnosis and treatment, cancer is still a big threat to our society (Kotnis et al, 2005). This is the second most common disease after cardiovascular disorders for maximum deaths in the world (Jemal et al, 2007). It accounts for about 23 and 7% deaths in USA and India, respectively. The world’s population is expected to be 7.5 billion by 2020 and approximations predict that about 15.0 million new cancer cases will be diagnosed; with deaths of about 12.0 million cancer patients (Brayand et al, 2006). The prevalence of cancer in India is estimated to be around 2.5 million, with about 8, 00,000 new cases and 5, 50,000 deaths per annum (Nandakumar, 1990-96). According to 1991 Indian census data, about 609000 cancer cases have been observed. This number had drastically increased to 806,000 by the end of the last century; with 96.4 and 88.2% age standardized rates for males and females; out of 100,000 cases analyzed (Rao et al, 1998). During last one decade, about 70% cancer cases have been diagnosed and treated with survival of a few patients (Dinshaw et al, 1999). It is believed that in near future the number of cancer patients will increase in the developing and under developed countries, which may rise up to 70%; a serious issue for all of us. The magnitude of cancer problem in the Indian Sub-continent (sheer numbers) is increasing due to poor to moderate living standards (Wynder et al, 1974) and inadequate medical facilities. Most frequently observed cancers in Indian population are of lungs, breast, colon, rectum, stomach and liver (Nandakumar, 1990-96; Rao et al, 1998; Murthy et al, 2004). Nowadays, India is growing with a good progress rate and probably will become a developed country within a few decades resulting into its participation in the world development. Therefore, it is important to study the status of cancers in India so that advance measures may be taken to control this havoc in near future. In view of these facts, attempts have been made to study the status of cancers in India including its causes, preventive measures, effect on Indian economy and comparison with global scenario.
MODULES
The methodology to reduce cancer is to study the status of cancers in India so that advance measures may be taken to control.
Cancer scenario in India: Based on the increasing trends of cancer patients during the last few decades, the numbers of cancer patients have been predicted by the end of 2015 and 2020 in India. These compiled data show that the number of male, female and the total cancer patients in 2004 were 390809, 428545 and 819354 respectively. The number of male and female cancer patients increased continuously up to 2009, with 454842, 507990 and 962832 cases for male, female and total cancer patients, respectively. Similarly, 462408 male cancer patients and 517378 female cancer patients were recorded, with a total number of 979786 patients in 2010. Thus, it is clear from this Figure that the number of cancer cases has increased gradually with time. Moreover, a prediction of cancer patients in 2015 and 2020, respectively, has also been made.
The different types of cancers observed in India are Lung cancer, Breast cancer, Stomach cancer, Gall bladder cancer, Cervical cancer, Oral cancer, Miscellaneous cancers.
Indian states and cancers: The most effected states of India due to this cancer are Jammu & Kashmir, Himachal Pradesh, Delhi, Uttarakhand, Rajasthan, Maharashtra, Jharkhand, West Bengal, Andhra Pradesh, Kerala, Tripura and Manipur. It is also clear from this Figure that cervical cancer is the second most common form of malignancy in female population of Himachal Pradesh, Haryana, Rajasthan, Goa, Tamil Nadu, West Bengal while it stands at third position in females of Punjab, Andhra Pradesh and Uttar Pradesh. Breast cancer is the most common form of cancer in the women of Himachal Pradesh, Delhi, Rajasthan, Nagaland and Goa, and the second most common form of malignancy in females of Punjab, Maharashtra and Gujarat.
Cancer causes in India: The cancer causes in India are almost same as in other parts of the world. The chemical, biological and other environmental identities are responsible for uncontrolled and unorganized proliferation of cells (carcinogens). Basically, under special circumstances carcinogens interact with DNA of the normal cells resulting into a series of complex multistep processes responsible for uncontrolled cell proliferation or tumors (Carmaeia, 1993). The causes for cancers can be both either internal factors like inherited mutations, hormones, and immune conditions or environmental factors such as tobacco, diet, radiation, and other infectious agents. A significant variation of cancer has been reported due to life styles and food habits (Helbock et al, 1998). For example, Asians have 25 and 10 times lower incidences of prostate and breast cancers, respectively, as compared to Western countries which may be attributed to comparatively simple life styles adopted by Asians, and safe sexual practices.
Preventive measures of cancer in India: As per the proverb, “prevention is better than cure” the prevention strategies are crucial in cancer eradication. This approach offers a great public health concern and inexpensive long term method of cancer control. National Cancer Control Programme (started in 1975- 1976 in India) led to the development of Regional Cancer Centers (RCCs), a number of oncology wings in Medical Colleges; supported the purchase of teletherapy machines. District Cancer Control Programme was also initiated but could not result into sustainable and productive activity (National Cancer Control Programme). The education should focus on harmful effects of tobacco and discourage its use.
Algorithms:
ü Linear Regression
ü Naïve Baye’s Algorithm
ü K-NN Algorithm
ü Support Vector Machines

EXISTING SYSTEM
During last one decade, about 70% cancer cases have been diagnosed and treated with survival of a few patients (Dinshaw et al, 1999). It is believed that in near future the number of cancer patients will increase in the developing and under developed countries, which may rise up to 70%; a serious issue for all of us. The magnitude of cancer problem in the Indian Sub-continent (sheer numbers) is increasing due to poor to moderate living standards (Wynder et al, 1974) and inadequate medical facilities. Most frequently observed cancers in Indian population are of lungs, breast, colon, rectum, stomach and liver.
PROPOSED SYSTEM
India is growing with a good progress rate and probably will become a developed country within a few decades resulting into its participation in the world development. Therefore, it is important to study the status of cancers in India so that advance measures may be taken to control this havoc in near future. In view of these facts, attempts have been made to study the status of cancers in India including its causes, preventive measures, effect on Indian economy and comparison with global scenario.
In view of these facts, the present article describes the status of various types of cancers in India and its comparison at global level. Besides, attempts have been made to describe the main causes of cancer along with their preventive measures. In addition to this, efforts have also been made to predict the effect of increasing number of cancer patients on the Indian economy.
·       readFIPS.py: script to ensure that proper Census Tract codes are attached to each record in the table. In this case, the air emissions data was supplied with latitude and longitude coordinates for each facility. We used the FCC API to return the U.S. Census Bureau Census Block number (i.e. the 15 character FIPS Code) given the passed latitude and longitude for each facility.
·       airEmissions.py: script for processing and cleaning.
·       main.py file: to incorporate within the model and perform the linear regression perform using the ordinary least squares (OLS) method as provided by the statsmodel library found within the SciPy python package. We find that our cross-sectional air emissions data is heteroscedastic and therefore we run our OLS model using heteroscedastic standard errors by calling the HC0 method within statsmodel.
·       Found within the SciPy python package. We find that our cross-sectional air emissions data is heteroscedastic and therefore we run our OLS model using heteroscedastic standard errors by calling the HC0 method within statsmodel.

CONCLUSION
A careful reading of the above discussion in this article clearly indicates an increased number of cancer patients every year in India. Various factors responsible for cancer genesis have been discussed, which need to be controlled for their eradication. India is a growing country playing a crucial role in the development of the whole world, and, hence, needs special attention on this issue. We should create awareness among public about the cancer havoc and its prevention. The different programs should be started by Government and NGOs for creating awareness among Indian public. The diet and living style are important factors to control the spreading of cancers and, hence, Indians should be careful about these facts. Briefly, cancer is disturbing the growing economy of the country, which can be saved by proper handling of this disease. In view of these facts, it is very important to eradicate this havoc. Let us hope for the best future of this country, which is playing an essential role in the development of the whole world.

BIBLIOGRAPHY
1.    Abegunde D, Mathers C, Adam T, Ortegon M, Strong K (2007) The burden and costs of chronic diseases in lowincome and middle-income countries. The Lancet 370,1929-38.
2.    Alabaster O (1972) Colorectal Cancer: Epidemiology risks and prevention. JP Lippincott, Philadelphia.
3.    Ali I, Rahis-ud-din, Saleem k, Aboul-Enein HY, Rather MA (2011) Social Aspects of Cancer Genesis. Cancer Therapy 8, 6-14

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